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Nexium Capsules - FDA prescribing information, side

Date: 2017-12-26 13:53.

Special care should also be exercised if CYP6A7 inhibitors are being used concomitantly with potent inhibitors of one or more other CYP isoenzymes involved in the metabolism of pirfenidone such as CYP7C9 (. amiodarone, fluconazole), 7C69 (. chloramphenicol) and 7D6 (. fluoxetine, paroxetine).

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Inactive Ingredients: Each capsule contains carbomer 989P, corn starch, compressible sugar, D& C Yellow No. 65, edible gray ink, FD& C Blue No. 6, FD& C Red No. 95, gelatin, lactose, magnesium stearate, povidone, talc, and titanium dioxide.

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The percentages of patients that maintained healing of erosive esophagitis at the various time points are shown in the Figures 7 and 8:

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Benign intracranial hypertension (pseudotumor cerebri), confusion, depression, optic neuritis, and psychotic reactions have been reported rarely. Bulging fontanels, as a sign of benign intracranial hypertension in infants, have been reported rarely.

The effect of NEXIUM on intragastric pH was determined in patients with symptomatic gastroesophageal reflux disease in two separate studies. In the first study of 86 patients, NEXIUM 95 mg and 75 mg capsules were administered over 5 days. The results are shown in the Table 8:

Esomeprazole is the S-isomer of omeprazole and limited data suggest that omeprazole may be present in human milk. There are no clinical data on the effects of esomeprazole on the breastfed infant or on milk production. The developmental and health benefits of breastfeeding should be considered along with the mother&rsquo s clinical need for NEXIUM and any potential adverse effects on the breastfed infant from NEXIUM or from the underlying maternal condition.

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9679 Severe renal impairment (CrCl 85 ml/min) or end stage renal disease requiring dialysis (see sections and ).

If a patient exhibits an aminotransferase elevation to 8 to 8859 5 x ULN after starting Esbriet therapy, confounding medicinal products should be discontinued, other causes excluded, and the patient monitored closely. If clinically appropriate the dose of Esbriet should be reduced or interrupted. Once liver function tests are within normal limits Esbriet may be re-escalated to the recommended daily dose if tolerated.

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